In Silico Analysis of Mechanisms of Maribavir-Induced Inhibition and Drug Resistance Mutations in pUL97 Kinase Structural Prediction with AlphaFold2

Infections with cytomegalovirus (CMV) can result in increased morbidity and mortality in immunocompromised patients. The pUL97 kinase is a critical enzyme in the regulation of CMV replication. Although it does not phosphorylate deoxynucleosides, this enzyme is involved in the first phosphorylation s...

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Bibliographic Details
Main Authors: Jocelyne Piret, Guy Boivin
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Viruses
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Online Access:https://www.mdpi.com/1999-4915/17/7/941
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