Nucleosides 8 [18]: Ribosylation of Fused Quinazolines—Synthesis of New [1,2,4]Triazolo[5,1-b]- and [1,2,4]Triazino[3,2-b]quinazoline Nucleosides of Fluorescence Interest
[1,2,4]Triazolo[5,1-b]- and [1,2,4]triazino[3,2-b] quinazolines have been ribosylated by coupling with 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose and by using the silylation method, followed by debenzoylation by methanolic sodium methoxide to afford the corresponding free N-nucleosides. Nucleos...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2013/612756 |
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| author | Laila Mohamed Break Mosselhi Abdelnabi Mosselhi Nagi Mohamed Elshafai |
| author_facet | Laila Mohamed Break Mosselhi Abdelnabi Mosselhi Nagi Mohamed Elshafai |
| author_sort | Laila Mohamed Break |
| collection | DOAJ |
| description | [1,2,4]Triazolo[5,1-b]- and [1,2,4]triazino[3,2-b] quinazolines have been ribosylated by coupling with 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose and by using the silylation method, followed by debenzoylation by methanolic sodium methoxide to afford the corresponding free N-nucleosides. Nucleosides obtained have been identified by their spectral analysis. From the UV-visible and fluorescence studies of some nucleosides synthesized, it is found that they have fluorescence properties. |
| format | Article |
| id | doaj-art-bbb1085cb1b048ce81cf91a2c63f25a1 |
| institution | Kabale University |
| issn | 2090-9063 2090-9071 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-bbb1085cb1b048ce81cf91a2c63f25a12025-02-03T01:32:02ZengWileyJournal of Chemistry2090-90632090-90712013-01-01201310.1155/2013/612756612756Nucleosides 8 [18]: Ribosylation of Fused Quinazolines—Synthesis of New [1,2,4]Triazolo[5,1-b]- and [1,2,4]Triazino[3,2-b]quinazoline Nucleosides of Fluorescence InterestLaila Mohamed Break0Mosselhi Abdelnabi Mosselhi1Nagi Mohamed Elshafai2Department of Chemistry, Faculty of Science (Girls), Taif University, P.O. Box 58, Taif, Saudi ArabiaDepartment of Chemistry, Faculty of Science, Taif University, Taif 888, Saudi ArabiaDepartment of Chemistry, Faculty of Science, Kafr El-Sheikh University, Kafr El-Sheikh City, Egypt[1,2,4]Triazolo[5,1-b]- and [1,2,4]triazino[3,2-b] quinazolines have been ribosylated by coupling with 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose and by using the silylation method, followed by debenzoylation by methanolic sodium methoxide to afford the corresponding free N-nucleosides. Nucleosides obtained have been identified by their spectral analysis. From the UV-visible and fluorescence studies of some nucleosides synthesized, it is found that they have fluorescence properties.http://dx.doi.org/10.1155/2013/612756 |
| spellingShingle | Laila Mohamed Break Mosselhi Abdelnabi Mosselhi Nagi Mohamed Elshafai Nucleosides 8 [18]: Ribosylation of Fused Quinazolines—Synthesis of New [1,2,4]Triazolo[5,1-b]- and [1,2,4]Triazino[3,2-b]quinazoline Nucleosides of Fluorescence Interest Journal of Chemistry |
| title | Nucleosides 8 [18]: Ribosylation of Fused Quinazolines—Synthesis of New [1,2,4]Triazolo[5,1-b]- and [1,2,4]Triazino[3,2-b]quinazoline Nucleosides of Fluorescence Interest |
| title_full | Nucleosides 8 [18]: Ribosylation of Fused Quinazolines—Synthesis of New [1,2,4]Triazolo[5,1-b]- and [1,2,4]Triazino[3,2-b]quinazoline Nucleosides of Fluorescence Interest |
| title_fullStr | Nucleosides 8 [18]: Ribosylation of Fused Quinazolines—Synthesis of New [1,2,4]Triazolo[5,1-b]- and [1,2,4]Triazino[3,2-b]quinazoline Nucleosides of Fluorescence Interest |
| title_full_unstemmed | Nucleosides 8 [18]: Ribosylation of Fused Quinazolines—Synthesis of New [1,2,4]Triazolo[5,1-b]- and [1,2,4]Triazino[3,2-b]quinazoline Nucleosides of Fluorescence Interest |
| title_short | Nucleosides 8 [18]: Ribosylation of Fused Quinazolines—Synthesis of New [1,2,4]Triazolo[5,1-b]- and [1,2,4]Triazino[3,2-b]quinazoline Nucleosides of Fluorescence Interest |
| title_sort | nucleosides 8 18 ribosylation of fused quinazolines synthesis of new 1 2 4 triazolo 5 1 b and 1 2 4 triazino 3 2 b quinazoline nucleosides of fluorescence interest |
| url | http://dx.doi.org/10.1155/2013/612756 |
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