Organocatalyzed diastereo- and enantioselective synthesis of N–N atropisomeric isoindolinones bearing central chirality

Abstract Methods for catalytically constructing of N–N axially chiral scaffolds have garnered significant attention since such compounds are widely present in natural products, bioactive molecules, and organic materials. Herein, we report a highly diastereoselective and enantioselective organocataly...

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Bibliographic Details
Main Authors: Xingguang Li, Xin-Ze Wang, Boming Shen, Qian-Yu Chen, Huijing Xiang, Peiyuan Yu, Pei-Nian Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56838-2
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