Perioperative gum-chewing training prevents a decrease in tongue pressure after esophagectomy in thoracic esophageal cancer patients: a nonrandomized trial
Abstract Tongue pressure (TP) decreases significantly after esophagectomy in esophageal cancer patients (ECPs). Meanwhile, 2 weeks of gum-chewing training (GCT) significantly increased TP in healthy university students. We examined whether perioperative GCT would decrease the proportion of patients...
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Nature Portfolio
2024-10-01
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| Online Access: | https://doi.org/10.1038/s41598-024-74090-4 |
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| author | Reiko Yamanaka-Kohno Yasuhiro Shirakawa Aya Yokoi Naoaki Maeda Shunsuke Tanabe Kazuhiro Noma Kazuyoshi Shimizu Toshiharu Mituhashi Yoshihide Nakamura Souto Nanba Yurika Uchida Takayuki Maruyama Manabu Morita Daisuke Ekuni |
| author_facet | Reiko Yamanaka-Kohno Yasuhiro Shirakawa Aya Yokoi Naoaki Maeda Shunsuke Tanabe Kazuhiro Noma Kazuyoshi Shimizu Toshiharu Mituhashi Yoshihide Nakamura Souto Nanba Yurika Uchida Takayuki Maruyama Manabu Morita Daisuke Ekuni |
| author_sort | Reiko Yamanaka-Kohno |
| collection | DOAJ |
| description | Abstract Tongue pressure (TP) decreases significantly after esophagectomy in esophageal cancer patients (ECPs). Meanwhile, 2 weeks of gum-chewing training (GCT) significantly increased TP in healthy university students. We examined whether perioperative GCT would decrease the proportion of patients exhibiting a decline in TP at 2 weeks postoperatively, and prevent postoperative complications, in thoracic ECPs (TECPs). This was a single-center interventional study, and nonrandomized study with a historical control group (HCG). TECPs who underwent first-stage radical esophagectomy were recruited. Thirty-two patients of 40 in the gum-chewing group (GCG) were completed perioperative GCT in 3 times daily. Propensity score matching was performed with covariates related to TP including preoperative age, sex, body mass index, and the repetitive saliva swallowing test result, and yielded a matched cohort of 25 case pairs. Eleven GCG patients [44.0%] exhibited significantly lower TP at 2 weeks postoperatively than before esophagectomy was significantly fewer than that of 19 patients [76.0%] in the HCG. The median number of fever days (≥ 38.0 °C) in the 2 weeks after esophagectomy in the GCG was significantly fewer than those in the HCG. Perioperative GCT may prevent postoperative TP decline and postoperative dysphagia-related complications after esophagectomy. |
| format | Article |
| id | doaj-art-bb4d73c6232147b9adee7718ebd41eec |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-bb4d73c6232147b9adee7718ebd41eec2025-02-02T12:25:18ZengNature PortfolioScientific Reports2045-23222024-10-011411910.1038/s41598-024-74090-4Perioperative gum-chewing training prevents a decrease in tongue pressure after esophagectomy in thoracic esophageal cancer patients: a nonrandomized trialReiko Yamanaka-Kohno0Yasuhiro Shirakawa1Aya Yokoi2Naoaki Maeda3Shunsuke Tanabe4Kazuhiro Noma5Kazuyoshi Shimizu6Toshiharu Mituhashi7Yoshihide Nakamura8Souto Nanba9Yurika Uchida10Takayuki Maruyama11Manabu Morita12Daisuke Ekuni13Department of Preventive Dentistry, Division of Dentistry, Okayama University HospitalDepartment of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical ScienceDepartment of Preventive Dentistry, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityDepartment of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical ScienceDepartment of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical ScienceDepartment of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical ScienceDepartment of Anesthesiology and Resuscitology, Okayama University HospitalCenter for Innovative Clinical Medicine, Okayama University HospitalDepartment of Oral and Maxillofacial Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical ScienceDental Clinic, Kurashiki Medical Check-Up CenterDepartment of Preventive Dentistry, Division of Dentistry, Okayama University HospitalDepartment of Preventive Dentistry, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityDepartment of Oral Health Sciences, Takarazuka University of Medical and Health CareDepartment of Preventive Dentistry, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityAbstract Tongue pressure (TP) decreases significantly after esophagectomy in esophageal cancer patients (ECPs). Meanwhile, 2 weeks of gum-chewing training (GCT) significantly increased TP in healthy university students. We examined whether perioperative GCT would decrease the proportion of patients exhibiting a decline in TP at 2 weeks postoperatively, and prevent postoperative complications, in thoracic ECPs (TECPs). This was a single-center interventional study, and nonrandomized study with a historical control group (HCG). TECPs who underwent first-stage radical esophagectomy were recruited. Thirty-two patients of 40 in the gum-chewing group (GCG) were completed perioperative GCT in 3 times daily. Propensity score matching was performed with covariates related to TP including preoperative age, sex, body mass index, and the repetitive saliva swallowing test result, and yielded a matched cohort of 25 case pairs. Eleven GCG patients [44.0%] exhibited significantly lower TP at 2 weeks postoperatively than before esophagectomy was significantly fewer than that of 19 patients [76.0%] in the HCG. The median number of fever days (≥ 38.0 °C) in the 2 weeks after esophagectomy in the GCG was significantly fewer than those in the HCG. Perioperative GCT may prevent postoperative TP decline and postoperative dysphagia-related complications after esophagectomy.https://doi.org/10.1038/s41598-024-74090-4Esophageal cancerEsophagectomyGum-chewing trainingTongue pressureHistorical controlPropensity score matching analysis |
| spellingShingle | Reiko Yamanaka-Kohno Yasuhiro Shirakawa Aya Yokoi Naoaki Maeda Shunsuke Tanabe Kazuhiro Noma Kazuyoshi Shimizu Toshiharu Mituhashi Yoshihide Nakamura Souto Nanba Yurika Uchida Takayuki Maruyama Manabu Morita Daisuke Ekuni Perioperative gum-chewing training prevents a decrease in tongue pressure after esophagectomy in thoracic esophageal cancer patients: a nonrandomized trial Scientific Reports Esophageal cancer Esophagectomy Gum-chewing training Tongue pressure Historical control Propensity score matching analysis |
| title | Perioperative gum-chewing training prevents a decrease in tongue pressure after esophagectomy in thoracic esophageal cancer patients: a nonrandomized trial |
| title_full | Perioperative gum-chewing training prevents a decrease in tongue pressure after esophagectomy in thoracic esophageal cancer patients: a nonrandomized trial |
| title_fullStr | Perioperative gum-chewing training prevents a decrease in tongue pressure after esophagectomy in thoracic esophageal cancer patients: a nonrandomized trial |
| title_full_unstemmed | Perioperative gum-chewing training prevents a decrease in tongue pressure after esophagectomy in thoracic esophageal cancer patients: a nonrandomized trial |
| title_short | Perioperative gum-chewing training prevents a decrease in tongue pressure after esophagectomy in thoracic esophageal cancer patients: a nonrandomized trial |
| title_sort | perioperative gum chewing training prevents a decrease in tongue pressure after esophagectomy in thoracic esophageal cancer patients a nonrandomized trial |
| topic | Esophageal cancer Esophagectomy Gum-chewing training Tongue pressure Historical control Propensity score matching analysis |
| url | https://doi.org/10.1038/s41598-024-74090-4 |
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