The Functional Characterization of Venous Thromboembolic Disease (FUVID) study: rationale, design, and methods of a prospective, observational, multicenter study to evaluate mechanisms of exercise intolerance and dyspnea following pediatric pulmonary embolism

The Functional Characterization of Venous Thromboembolic Disease (FUVID) study: rationale, design, and methods of a prospective, observational, multicenter study to evaluate mechanisms of exercise intolerance and dyspnea following pediatric pulmonary embolism

Background: To date, the focus of investigation in pediatric pulmonary embolism (PE) has been on PE recurrence and anticoagulant-related bleeding. While highly relevant, these outcomes do not fully capture functional limitations and the psychological impact that comprises post-PE syndrome. Objective...

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Main Authors: Ayesha Zia, Michael D. Nelson, Jimin Ren, Song Zhang, Robert F. Mattrey, Brian L. Han, Tarique Hussain, Joshua S. Greer, Manal Al-Qahtani, Kendra Malone, Sonja E. Stutzman, Deseray V. Sida, Sharon Primeaux, Marcela D. Torres, Clay T. Cohen, Shelley Crary, Jonathan Bernstein, Hilary B. Whitworth, Riten Kumar, Kisha A. Beg, Osman Khan, Madhvi Rajpurkar, Kerry Hege, Beverly A. Schaefer, Gary M. Woods, Lauren E. Amos, Marisol Betensky, Rukhmi V. Bhat, Sarah O’ Brien, Julie Jaffray, Rohit Jesudas, Martha M. Pacheco, Cristina Tarango, Angela C. Weyand, Hope P. Wilson, Jessica Garcia, Mary P. Dang, Ruchika Sharma, Neil A. Goldenberg, Frederikus A. Klok, Christoph Male, Benjamin Levine, Bryce N. Balmain, Tony G. Babb, Leah M. Adix, BS, Steven Ambrusko, MD, Shames Alaesa, BSc, Kristen Bradley, BSN, RN, Brain R. Branchford, MD, Katie Carlberg, MD, James D. Cooper, MD, Susan A. Corley, MPH, Marissa Di Miero, MBA, Anna Eidenberger, Edith Freyer, DNP, Kevin Guerrero, Arun Gurunathan, MD, Brandon Hathorn, BSc, Muhammad Khan, Shawn D. Lade, BS, Deanna M. Maida, MD, Marie Martinelli, MD, Corey Mozingo, BS, Raksa Moran, RN, Sharon A. Primeaux, MS, Leslie Raffini, MD, MSCE, Rhea Robinson, BSN, Cynthia Sabo, MSN, Negin Saleh, Anjali A. Sharathkumar, MBBS, MD, MS, Rachel Simon, DNP, APRN, CPNP-PC, Lakshmi Srivaths, MD, MacKenzie Tasset, BS, Katrina Williams, BS, Rebekah Summerall Woodward, MPH, Neil A. Goldenberg, MD, PhD, Frederikus A. Klok, MD, PhD, Christoph Male, MS, MSc, Tony G. Babb, PhD, Madhvi Rajpurkar, MD, Song Zhang, PhD
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
children
pediatrics
pulmonary embolism
post–pulmonary embolism syndrome
venous thromboembolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2475037924003649
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