Exposure-response analyses of venetoclax combined with hypomethylating agents in myelodysplastic syndromes: a retrospective study

BackgroundVenetoclax (VEN), an orally bioavailable B-cell lymphoma-2 inhibitor, shows promising activity in patients with myelodysplastic syndromes (MDS) when combined with hypomethylating agents (HMAs). However, research regarding the VEN exposure in Chinese patients with MDS remains notably sparse...

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Bibliographic Details
Main Authors: Ji-Xin Tian, Ping Zhang, Xiao-Xu Wang, Jin-Wen Li, Dong-Xue Liu, Yi-Ying Liu, Zhi-Jian Xiao, Wen-Juan Miao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1586910/full
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