Metformin Delays Satellite Cell Activation and Maintains Quiescence

The regeneration of the muscle tissue relies on the capacity of the satellite stem cell (SC) population to exit quiescence, divide asymmetrically, proliferate, and differentiate. In age-related muscle atrophy (sarcopenia) and several dystrophies, regeneration cannot compensate for the loss of muscle...

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Bibliographic Details
Main Authors: Theodora Pavlidou, Milica Marinkovic, Marco Rosina, Claudia Fuoco, Simone Vumbaca, Cesare Gargioli, Luisa Castagnoli, Gianni Cesareni
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2019/5980465
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