Reference Intervals of Total Testosterone in Adult Filipino Men

Background. The reference range of total testosterone needs to be established locally as ethnic differences in adiposity, insulin sensitivity, and sex hormone-binding globulin (SHBG) levels may affect total testosterone levels. The aim of this study is to establish the reference intervals of total t...

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Main Authors: Myrna Buenaluz‐Sedurante, Mark Isaiah K. Co, Daryl Jade T. Dagang, Racquel G. Bruno, Annie Jane N. Sarmiento, Michael L. Tee
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2020/8877261
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author Myrna Buenaluz‐Sedurante
Mark Isaiah K. Co
Daryl Jade T. Dagang
Racquel G. Bruno
Annie Jane N. Sarmiento
Michael L. Tee
author_facet Myrna Buenaluz‐Sedurante
Mark Isaiah K. Co
Daryl Jade T. Dagang
Racquel G. Bruno
Annie Jane N. Sarmiento
Michael L. Tee
author_sort Myrna Buenaluz‐Sedurante
collection DOAJ
description Background. The reference range of total testosterone needs to be established locally as ethnic differences in adiposity, insulin sensitivity, and sex hormone-binding globulin (SHBG) levels may affect total testosterone levels. The aim of this study is to establish the reference intervals of total testosterone from healthy, young adult Filipino males. Methods. The study included 110 healthy, Filipino male volunteers aged 21–40, studying or working at the University of the Philippines Manila. Clinical history, height, weight, body mass index (BMI), and blood pressure (BP) were obtained, and blood for total testosterone, SHBG, albumin, insulin, fasting blood sugar (FBS), and total cholesterol was collected. Free testosterone was calculated using Vermeulen’s formula. The 2.5th to 97.5th percentiles of subjects for total testosterone were used as the normative range for Filipino men. Results. The reference range of total testosterone is 7.33–53.01 nmol/L. Conclusion. The present study derived reference ranges of total testosterone using data from apparently healthy, young adult men to support clinical services.
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spelling doaj-art-ba7d2634b6e542d6a27d89fe03c533632025-02-03T01:08:11ZengWileyInternational Journal of Endocrinology1687-83371687-83452020-01-01202010.1155/2020/88772618877261Reference Intervals of Total Testosterone in Adult Filipino MenMyrna Buenaluz‐Sedurante0Mark Isaiah K. Co1Daryl Jade T. Dagang2Racquel G. Bruno3Annie Jane N. Sarmiento4Michael L. Tee5Department of Physiology, University of the Philippines College of Medicine, Manila, PhilippinesDivision of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of the Philippines College of Medicine, Manila, PhilippinesDivision of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of the Philippines College of Medicine, Manila, PhilippinesDivision of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of the Philippines College of Medicine, Manila, PhilippinesDivision of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of the Philippines College of Medicine, Manila, PhilippinesDepartment of Physiology, University of the Philippines College of Medicine, Manila, PhilippinesBackground. The reference range of total testosterone needs to be established locally as ethnic differences in adiposity, insulin sensitivity, and sex hormone-binding globulin (SHBG) levels may affect total testosterone levels. The aim of this study is to establish the reference intervals of total testosterone from healthy, young adult Filipino males. Methods. The study included 110 healthy, Filipino male volunteers aged 21–40, studying or working at the University of the Philippines Manila. Clinical history, height, weight, body mass index (BMI), and blood pressure (BP) were obtained, and blood for total testosterone, SHBG, albumin, insulin, fasting blood sugar (FBS), and total cholesterol was collected. Free testosterone was calculated using Vermeulen’s formula. The 2.5th to 97.5th percentiles of subjects for total testosterone were used as the normative range for Filipino men. Results. The reference range of total testosterone is 7.33–53.01 nmol/L. Conclusion. The present study derived reference ranges of total testosterone using data from apparently healthy, young adult men to support clinical services.http://dx.doi.org/10.1155/2020/8877261
spellingShingle Myrna Buenaluz‐Sedurante
Mark Isaiah K. Co
Daryl Jade T. Dagang
Racquel G. Bruno
Annie Jane N. Sarmiento
Michael L. Tee
Reference Intervals of Total Testosterone in Adult Filipino Men
International Journal of Endocrinology
title Reference Intervals of Total Testosterone in Adult Filipino Men
title_full Reference Intervals of Total Testosterone in Adult Filipino Men
title_fullStr Reference Intervals of Total Testosterone in Adult Filipino Men
title_full_unstemmed Reference Intervals of Total Testosterone in Adult Filipino Men
title_short Reference Intervals of Total Testosterone in Adult Filipino Men
title_sort reference intervals of total testosterone in adult filipino men
url http://dx.doi.org/10.1155/2020/8877261
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