coiaf: Directly estimating complexity of infection with allele frequencies.

In malaria, individuals are often infected with different parasite strains. The complexity of infection (COI) is defined as the number of genetically distinct parasite strains in an individual. Changes in the mean COI in a population have been shown to be informative of changes in transmission inten...

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Bibliographic Details
Main Authors: Aris Paschalidis, Oliver J Watson, Ozkan Aydemir, Robert Verity, Jeffrey A Bailey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-06-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010247
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