Peptides targeting RAB11A–FIP2 complex inhibit HPIV3, RSV, and IAV replication as broad-spectrum antivirals

Peptides targeting RAB11A–FIP2 complex inhibit HPIV3, RSV, and IAV replication as broad-spectrum antivirals

Abstract Background The cytoskeletal framework plays a critical role in the early stages of human parainfluenza virus type 3 (HPIV3) replication, including viral mRNA synthesis and translation. However, its contribution to later stages of infection, particularly in the context of RNA biology, is not...

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Bibliographic Details
Main Authors: Yanliang Jiang, Yongliang Zhao, Jie Deng, Xiaoyan Wu, Jian Li, Dong Guo, Ke Xu, Yali Qin, Mingzhou Chen
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Cell & Bioscience
Subjects:
HPIV3
RSV
IAV
RAB11A
YT-DRI
Cytoskeletal framework
Online Access:https://doi.org/10.1186/s13578-025-01384-z
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