IL-18-primed NK cells recruit dendritic cells and potentiate tumor therapy mediated by PD-1 blockade
The success of cancer immunotherapy depends on the effective coordination of innate and adaptive immunity. We previously reported that IL-18 potentiates the therapeutic effects of immune checkpoint inhibitors in mouse models. Here, we report that IL-18-primed natural killer (NK) cells enhanced the a...
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| Main Authors: | Yoshiya Ohno, Haruki Okamura, Hideo Yagita, Toshiyuki Tanaka |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-03-01
|
| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2025.1533808/full |
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