Transcriptome Data Combined With Mendelian Randomization Analysis Identifies Key Genes Associated With Mitochondria and Programmed Cell Death in Intervertebral Disc Degeneration

ABSTRACT Background Intervertebral disc degeneration (IDD) is a major cause of cervical and lumbar diseases, significantly impacting patients' quality of life. Mitochondria and cell death have been implicated in IDD, but the key related genes remain unknown. Methods Differentially expressed gen...

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Bibliographic Details
Main Authors: Hongfei Nie, Xiao Hu, Jiaxiao Wang, Jia Wang, Xiaoqian Yu, Jun Li
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:JOR Spine
Subjects:
Online Access:https://doi.org/10.1002/jsp2.70057
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