Asymmetrical labium majus enlargement (CALME) in childhood: A series of clinical cases

Childhood asymmetry labium majus enlargement (CALME) is a rare, benign disease of pre-pubertal age characterized by non-neoplastic unilateral proliferation of the soft tissues of the vulva without a peripheral capsule. The pathogenesis of CALME is not completely clear. Generally, the only treatment...

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Main Authors: Zalina K. Batyrova, Zaira Kh. Kymykova, Elena V. Uvarova, Alina S. Badlaeva, Aleksandra V. Asaturova, Polina V. Kulabukhova, Fatima Sh. Mamedova, Vladimir D. Chuprynin, Irina A. Yagovkina
Format: Article
Language:Russian
Published: IP Berlin A.V. 2024-12-01
Series:Гинекология
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Online Access:https://gynecology.orscience.ru/2079-5831/article/viewFile/633248/pdf
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author Zalina K. Batyrova
Zaira Kh. Kymykova
Elena V. Uvarova
Alina S. Badlaeva
Aleksandra V. Asaturova
Polina V. Kulabukhova
Fatima Sh. Mamedova
Vladimir D. Chuprynin
Irina A. Yagovkina
author_facet Zalina K. Batyrova
Zaira Kh. Kymykova
Elena V. Uvarova
Alina S. Badlaeva
Aleksandra V. Asaturova
Polina V. Kulabukhova
Fatima Sh. Mamedova
Vladimir D. Chuprynin
Irina A. Yagovkina
author_sort Zalina K. Batyrova
collection DOAJ
description Childhood asymmetry labium majus enlargement (CALME) is a rare, benign disease of pre-pubertal age characterized by non-neoplastic unilateral proliferation of the soft tissues of the vulva without a peripheral capsule. The pathogenesis of CALME is not completely clear. Generally, the only treatment method is surgery because it is necessary to verify the diagnosis and exclude the neoplastic process. Most studies indicate the benign nature of CALME and the importance of a non-surgical approach if specific diagnostic criteria are met. The article presents clinical observations of CALME syndrome in girls, taking into account the modern differentiated approach to the management of patients with this disorder.
format Article
id doaj-art-b9ad74c6790e448cbe99de1ca09cf16b
institution Kabale University
issn 2079-5696
2079-5831
language Russian
publishDate 2024-12-01
publisher IP Berlin A.V.
record_format Article
series Гинекология
spelling doaj-art-b9ad74c6790e448cbe99de1ca09cf16b2025-01-21T20:47:29ZrusIP Berlin A.V.Гинекология2079-56962079-58312024-12-0126436336710.26442/20795696.2024.4.20303679607Asymmetrical labium majus enlargement (CALME) in childhood: A series of clinical casesZalina K. Batyrova0https://orcid.org/0000-0003-4997-6090Zaira Kh. Kymykova1https://orcid.org/0000-0001-7511-1432Elena V. Uvarova2https://orcid.org/0000-0002-3105-5640Alina S. Badlaeva3https://orcid.org/0000-0001-5223-9767Aleksandra V. Asaturova4https://orcid.org/0000-0001-8739-5209Polina V. Kulabukhova5https://orcid.org/0000-0002-0363-3669Fatima Sh. Mamedova6https://orcid.org/0000-0003-1136-7222Vladimir D. Chuprynin7https://orcid.org/0000-0002-2997-9019Irina A. Yagovkina8https://orcid.org/0009-0000-5121-9609Kulakov National Medical Research Center for Obstetrics, Gynecology and PerinatologyKulakov National Medical Research Center for Obstetrics, Gynecology and PerinatologyKulakov National Medical Research Center for Obstetrics, Gynecology and PerinatologyKulakov National Medical Research Center for Obstetrics, Gynecology and PerinatologyKulakov National Medical Research Center for Obstetrics, Gynecology and PerinatologyKulakov National Medical Research Center for Obstetrics, Gynecology and PerinatologyKulakov National Medical Research Center for Obstetrics, Gynecology and PerinatologyKulakov National Medical Research Center for Obstetrics, Gynecology and PerinatologyKulakov National Medical Research Center for Obstetrics, Gynecology and PerinatologyChildhood asymmetry labium majus enlargement (CALME) is a rare, benign disease of pre-pubertal age characterized by non-neoplastic unilateral proliferation of the soft tissues of the vulva without a peripheral capsule. The pathogenesis of CALME is not completely clear. Generally, the only treatment method is surgery because it is necessary to verify the diagnosis and exclude the neoplastic process. Most studies indicate the benign nature of CALME and the importance of a non-surgical approach if specific diagnostic criteria are met. The article presents clinical observations of CALME syndrome in girls, taking into account the modern differentiated approach to the management of patients with this disorder.https://gynecology.orscience.ru/2079-5831/article/viewFile/633248/pdfcalmelabia majora asymmetryvulvapre-puberty agegirls
spellingShingle Zalina K. Batyrova
Zaira Kh. Kymykova
Elena V. Uvarova
Alina S. Badlaeva
Aleksandra V. Asaturova
Polina V. Kulabukhova
Fatima Sh. Mamedova
Vladimir D. Chuprynin
Irina A. Yagovkina
Asymmetrical labium majus enlargement (CALME) in childhood: A series of clinical cases
Гинекология
calme
labia majora asymmetry
vulva
pre-puberty age
girls
title Asymmetrical labium majus enlargement (CALME) in childhood: A series of clinical cases
title_full Asymmetrical labium majus enlargement (CALME) in childhood: A series of clinical cases
title_fullStr Asymmetrical labium majus enlargement (CALME) in childhood: A series of clinical cases
title_full_unstemmed Asymmetrical labium majus enlargement (CALME) in childhood: A series of clinical cases
title_short Asymmetrical labium majus enlargement (CALME) in childhood: A series of clinical cases
title_sort asymmetrical labium majus enlargement calme in childhood a series of clinical cases
topic calme
labia majora asymmetry
vulva
pre-puberty age
girls
url https://gynecology.orscience.ru/2079-5831/article/viewFile/633248/pdf
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