Neurogenic Bladder Repair Using Autologous Mesenchymal Stem Cells

The normal function of the urinary bladder is to store and expel urine in a coordinated, controlled fashion, the activity of which is regulated by the central and peripheral nervous systems. Neurogenic bladder is a term applied to a malfunctioning urinary bladder due to neurologic dysfunction or ins...

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Main Authors: Pradeep V. Mahajan, Swetha Subramanian, Amit Danke, Anand Kumar
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Urology
Online Access:http://dx.doi.org/10.1155/2016/2539320
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author Pradeep V. Mahajan
Swetha Subramanian
Amit Danke
Anand Kumar
author_facet Pradeep V. Mahajan
Swetha Subramanian
Amit Danke
Anand Kumar
author_sort Pradeep V. Mahajan
collection DOAJ
description The normal function of the urinary bladder is to store and expel urine in a coordinated, controlled fashion, the activity of which is regulated by the central and peripheral nervous systems. Neurogenic bladder is a term applied to a malfunctioning urinary bladder due to neurologic dysfunction or insult emanating from internal or external trauma, disease, or injury. This report describes a case of neurogenic bladder following laminectomy procedure and long-standing diabetes mellitus with neuropathy treated with autologous cellular therapy. The differentiation potential and paracrine effects of mesenchymal stem cells on bladder function have been highlighted.
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institution Kabale University
issn 2090-696X
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language English
publishDate 2016-01-01
publisher Wiley
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series Case Reports in Urology
spelling doaj-art-b997acaee4bd466ab3adb26599b7e7b42025-02-03T01:11:21ZengWileyCase Reports in Urology2090-696X2090-69782016-01-01201610.1155/2016/25393202539320Neurogenic Bladder Repair Using Autologous Mesenchymal Stem CellsPradeep V. Mahajan0Swetha Subramanian1Amit Danke2Anand Kumar3StemRx Bioscience Solutions Pvt. Ltd., Navi Mumbai, IndiaStemRx Bioscience Solutions Pvt. Ltd., Navi Mumbai, IndiaStemRx Bioscience Solutions Pvt. Ltd., Navi Mumbai, IndiaStemRx Bioscience Solutions Pvt. Ltd., Navi Mumbai, IndiaThe normal function of the urinary bladder is to store and expel urine in a coordinated, controlled fashion, the activity of which is regulated by the central and peripheral nervous systems. Neurogenic bladder is a term applied to a malfunctioning urinary bladder due to neurologic dysfunction or insult emanating from internal or external trauma, disease, or injury. This report describes a case of neurogenic bladder following laminectomy procedure and long-standing diabetes mellitus with neuropathy treated with autologous cellular therapy. The differentiation potential and paracrine effects of mesenchymal stem cells on bladder function have been highlighted.http://dx.doi.org/10.1155/2016/2539320
spellingShingle Pradeep V. Mahajan
Swetha Subramanian
Amit Danke
Anand Kumar
Neurogenic Bladder Repair Using Autologous Mesenchymal Stem Cells
Case Reports in Urology
title Neurogenic Bladder Repair Using Autologous Mesenchymal Stem Cells
title_full Neurogenic Bladder Repair Using Autologous Mesenchymal Stem Cells
title_fullStr Neurogenic Bladder Repair Using Autologous Mesenchymal Stem Cells
title_full_unstemmed Neurogenic Bladder Repair Using Autologous Mesenchymal Stem Cells
title_short Neurogenic Bladder Repair Using Autologous Mesenchymal Stem Cells
title_sort neurogenic bladder repair using autologous mesenchymal stem cells
url http://dx.doi.org/10.1155/2016/2539320
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AT swethasubramanian neurogenicbladderrepairusingautologousmesenchymalstemcells
AT amitdanke neurogenicbladderrepairusingautologousmesenchymalstemcells
AT anandkumar neurogenicbladderrepairusingautologousmesenchymalstemcells