A novel mast cell marker gene-related prognostic signature to predict prognosis and reveal the immune landscape in head and neck squamous cell carcinoma

A novel mast cell marker gene-related prognostic signature to predict prognosis and reveal the immune landscape in head and neck squamous cell carcinoma

BackgroundHead and neck squamous cell carcinoma (HNSCC) is a highly aggressive and heterogeneous malignant tumor. Mast cells are one of the immune cells widely distributed in the tumor microenvironment (TME), and their immune response with various immune cells is essential in promoting or inhibiting...

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Bibliographic Details
Main Authors: Yingmiao Lin, Fangcai Wu, Xuchun Huang, Zhihan Zhang, Cantong Liu, Yiwei Lin, Yiwei Xu, Haipeng Guo, Chaoqun Hong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
mast cell
head and neck squamous cell carcinoma
single-cell sequencing
immune infiltration
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1538641/full
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