Impact of c-JUN deficiency on thalamus development in mice and human neural models

Impact of c-JUN deficiency on thalamus development in mice and human neural models

Abstract Background c-Jun is a key regulator of gene expression. Through the formation of homo- or heterodimers, c-JUN binds to DNA and regulates gene transcription. While c-Jun plays a crucial role in embryonic development, its impact on nervous system development in higher mammals, especially for...

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Bibliographic Details
Main Authors: Jiantao Shi, Qing Chen, Jianheng Lai, Jieying Zhu, Ran Zhang, Md. Abdul Mazid, Dongwei Li, Huanxing Su, Dajiang Qin
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Cell & Bioscience
Subjects:
c-JUN
AP-1
NPC
Cerebral organoids
Thalamus organoids
Neural development
Online Access:https://doi.org/10.1186/s13578-024-01303-8
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https://doi.org/10.1186/s13578-024-01303-8

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