The pleiotropic effects of statins: a comprehensive exploration of neurovascular unit modulation and blood–brain barrier protection

The pleiotropic effects of statins: a comprehensive exploration of neurovascular unit modulation and blood–brain barrier protection

Abstract The blood–brain barrier (BBB) is the most central component of the neurovascular unit (NVU) and is crucial for the maintenance of the internal environment of the central nervous system and the regulation of homeostasis. A multitude of neuroprotective agents have been developed to exert neur...

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Main Authors: Jia-Cheng Liu, Shuang-Yin Lei, Dian-Hui Zhang, Qian-Yan He, Ying-Ying Sun, Hong-Jing Zhu, Yang Qu, Sheng-Yu Zhou, Yi Yang, Chao Li, Zhen-Ni Guo
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Molecular Medicine
Subjects:
Statins
Pleiotropic effects
Neurovascular unit
Blood–brain barrier
Ischemic stroke
Online Access:https://doi.org/10.1186/s10020-024-01025-0
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https://doi.org/10.1186/s10020-024-01025-0

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