Innate epithelial and functional differences in airway epithelium of children with acute wheeze

Innate epithelial and functional differences in airway epithelium of children with acute wheeze

BackgroundEarly childhood wheeze is a major risk factor for asthma. However, not all children who wheeze will develop the disease. The airway epithelium has been shown to be involved in asthma pathogenesis. Despite this, the airway epithelium of children with acute wheeze remains poorly characterize...

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Bibliographic Details
Main Authors: Kevin Looi, Thomas Iosifidis, Saraya Harrison, Stephen M. Stick, Peter LeSouef, Ingrid A. Laing, Anthony Kicic
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
acute wheeze
airway epithelium
barrier integrity
cell culture
conditional reprogramming
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1606915/full
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https://www.frontiersin.org/articles/10.3389/fcell.2025.1606915/full

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