The Jag2/Notch1 signaling axis promotes sebaceous gland differentiation and controls progenitor proliferation

The Jag2/Notch1 signaling axis promotes sebaceous gland differentiation and controls progenitor proliferation

The sebaceous gland (SG) is a vital appendage of the epidermis, and its normal homeostasis and function is crucial for effective maintenance of the skin barrier. Notch signaling is a well-known regulator of epidermal differentiation, and has also been shown to be involved in postnatal maintenance of...

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Bibliographic Details
Main Authors: Syeda Nayab Fatima Abidi, Sara Chan, Kerstin Seidel, Daniel Lafkas, Louis Vermeulen, Frank Peale, Christian W Siebel
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-11-01
Series:eLife
Subjects:
Notch signaling
therapeutic antibodies
cell fates
differentiation
Online Access:https://elifesciences.org/articles/98747
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https://elifesciences.org/articles/98747

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