Hypoxia-Induced Reactive Oxygen Species: Their Role in Cancer Resistance and Emerging Therapies to Overcome It

Normal tissues typically maintain partial oxygen pressure within a range of 3–10% oxygen, ensuring homeostasis through a well-regulated oxygen supply and responsive vascular network. However, in solid tumors, rapid growth often outpaces angiogenesis, creating a hypoxic microenvironment that fosters...

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Bibliographic Details
Main Authors: Eleicy Nathaly Mendoza, Maria Rosa Ciriolo, Fabio Ciccarone
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Antioxidants
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Online Access:https://www.mdpi.com/2076-3921/14/1/94
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