Hypoxia induces robust ATP release from erythrocytes in ApoE-LDLR double-deficient mice

Hypoxia induces robust ATP release from erythrocytes in ApoE-LDLR double-deficient mice

Red blood cells (RBCs) play a role in the regulation of vascular tone via release of adenosine triphosphate (ATP) into the vasculature in response to various stimuli. Interestingly, ApoE/LDLR double-deficient (ApoE/LDLR−/−) mice, a murine model of atherosclerosis, display a higher exercise capacity...

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Bibliographic Details
Main Authors: Fatih Celal Alcicek, Jakub Dybas, Katarzyna Bulat, Tasnim Mohaissen, Ewa Szczesny-Malysiak, Magdalena Franczyk-Zarow, Katarzyna M. Marzec
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Physiology
Subjects:
red blood cells
hemoglobin
ATP release
hypoxia
atherosclerosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2024.1497346/full
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