Benchmarking cell type annotation methods for 10x Xenium spatial transcriptomics data
Abstract Background Imaging-based spatial transcriptomics technologies allow us to explore spatial gene expression profiles at the cellular level. Cell type annotation of imaging-based spatial data is challenging due to the small gene panel, but it is a crucial step for downstream analyses. Many goo...
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Main Authors: | Jinming Cheng, Xinyi Jin, Gordon K. Smyth, Yunshun Chen |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-01-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-025-06044-0 |
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