Benchmarking cell type annotation methods for 10x Xenium spatial transcriptomics data

Abstract Background Imaging-based spatial transcriptomics technologies allow us to explore spatial gene expression profiles at the cellular level. Cell type annotation of imaging-based spatial data is challenging due to the small gene panel, but it is a crucial step for downstream analyses. Many goo...

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Bibliographic Details
Main Authors: Jinming Cheng, Xinyi Jin, Gordon K. Smyth, Yunshun Chen
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Bioinformatics
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Online Access:https://doi.org/10.1186/s12859-025-06044-0
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