A DFT investigation of the adsorption mechanism of paclitaxel on functionalized graphene oxide for enhanced drug delivery

Abstract The development of effective drug delivery systems is vital for enhancing the therapeutic efficacy of anticancer agents, particularly paclitaxel (PTX). Despite its potent anticancer properties, PTX faces limitations due to poor solubility and non-specific distribution, leading to significan...

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Bibliographic Details
Main Authors: Bader Huwaimel, Saad Alqarni
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-99156-9
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