Saturated lysing efficiency of CD8+ cells induced monostable, bistable and oscillatory HIV kinetics

Effector CD8+ cells lyse human immunodeficiency viruses (HIV)-infected CD4+ cells by recognizing a viral peptide presented by human leukocyte antigens (HLA) on the CD4+ cell surface, which plays an irreplaceable role in within-host HIV clearance. Using a semi-saturated lysing efficiency of a CD8+ ce...

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Bibliographic Details
Main Author: Shilian Xu
Format: Article
Language:English
Published: AIMS Press 2024-10-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2024324
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