Molecular mechanisms of glucose metabolism disorders in tumors of the female reproductive system

Molecular mechanisms of glucose metabolism disorders in tumors of the female reproductive system

Glucose metabolism plays a pivotal role in fueling the energetic and biosynthetic demands in rapidly proliferating cells. In gynecologic malignancies (GMs), including ovarian cancer (OC), endometrial cancer (EC), and cervical cancer (CC), metabolic reprogramming occurs to support tumor growth, invas...

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Main Authors: E. Yu. Kovaleva, R. R. Kantimirova, T. K. Gunina, E. V. Vlasenko, D. O. Salychin, D. S. Khulagova, A. Kochkin, V. A. Mamatkova, N. S. Zhakov, G. K. Bezmaternykh, E. Yu. Fomenko, A. A. Mullagalieva, F. S. Ali, R. N. Imanova
Format: Article
Language:Russian
Published: IRBIS LLC 2020-04-01
Series:Акушерство, гинекология и репродукция
Subjects:
glucose metabolism
gynecologic tumors
warburg effect
glycolysis
pentose phosphate pathway
metabolic enzymes
therapeutic targets
Online Access:https://www.gynecology.su/jour/article/view/2515
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https://www.gynecology.su/jour/article/view/2515

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