The microbial metabolite trimethylamine N-oxide and the kidney diseases

The microbial metabolite trimethylamine N-oxide and the kidney diseases

Trimethylamine N-oxide (TMAO), a metabolite, is a co-metabolite produced by both gut microbiota and livers, originating from foods rich in choline or carnitine. Emerging evidence suggests that TMAO may play a role in the pathogenesis of various kidney diseases, including acute kidney injury and chro...

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Bibliographic Details
Main Authors: Jin-Qi Su, Xiang-Qi Wu, Qi Wang, Bo-Yang Xie, Cui-Yan Xiao, Hong-Yong Su, Ji-Xin Tang, Cui-Wei Yao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
gut microbiome
TMAO
kidney injury
chronic kidney disease
end-stage renal disease
inflammatory mechanisms
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1488264/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2025.1488264/full

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