The tissue and circulating cell‐free DNA‐derived genetic landscape of premalignant colorectal lesions and its application for early diagnosis of colorectal cancer

The tissue and circulating cell‐free DNA‐derived genetic landscape of premalignant colorectal lesions and its application for early diagnosis of colorectal cancer

Abstract Colorectal adenomas (CRAs) represent precancerous lesions that precede the development of colorectal cancer (CRC). Regular monitoring of CRAs can hinder the progression into carcinoma. To explore the utility of tissue DNA and circulating cell‐free DNA (cfDNA) in early diagnosis of CRC, we r...

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Main Authors: Qingjian Chen, Yu‐Hong Xu, Shiyang Kang, WuHao Lin, Linna Luo, Luping Yang, Qi‐Hua Zhang, Pan Yang, Jia‐Qian Huang, Xiaoni Zhang, Jing Zhang, Qi Zhao, Rui‐Hua Xu, Hui‐Yan Luo
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:MedComm
Subjects:
circulating cell‐free DNA
colorectal adenomas
colorectal cancer
premalignant lesions
Online Access:https://doi.org/10.1002/mco2.70011
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https://doi.org/10.1002/mco2.70011

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