Cell cycle arrest of cardiomyocytes in the context of cardiac regeneration

Cell cycle arrest of cardiomyocytes in the context of cardiac regeneration

The limited capacity of adult mammalian cardiomyocytes to undergo cell division and proliferation is one of the key factors contributing to heart failure. In newborn mice, cardiac proliferation occurs during a brief window, but this proliferative capacity diminishes by 7 days after birth. Current st...

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Bibliographic Details
Main Authors: Qingling Xu, Xinhui Chen, Chunyige Zhao, Ying Liu, Jianxun Wang, Xiang Ao, Wei Ding
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
cardiomyocyte
proliferation
cardiac regeneration
cell cycle arrest
cardiovascular disease
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1538546/full
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