Comparative Analysis of the Safety and Functional Outcomes of Anterior versus Retropupillary Iris-Claw IOL Fixation

Purpose. To compare the functional and clinical outcomes of the iris-claw intraocular lens (IOL) placed on the anterior versus posterior surface of the iris. Patients and Methods. A multicenter, retrospective study. Data on eyes that underwent anterior or retropupillary iris-claw IOL implantation be...

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Main Authors: Paolo Mora, Giacomo Calzetti, Stefania Favilla, Matteo Forlini, Salvatore Tedesco, Purva Date, Viola Tagliavini, Arturo Carta, Rino Frisina, Emilio Pedrotti, Stefano Gandolfi
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2018/8463569
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author Paolo Mora
Giacomo Calzetti
Stefania Favilla
Matteo Forlini
Salvatore Tedesco
Purva Date
Viola Tagliavini
Arturo Carta
Rino Frisina
Emilio Pedrotti
Stefano Gandolfi
author_facet Paolo Mora
Giacomo Calzetti
Stefania Favilla
Matteo Forlini
Salvatore Tedesco
Purva Date
Viola Tagliavini
Arturo Carta
Rino Frisina
Emilio Pedrotti
Stefano Gandolfi
author_sort Paolo Mora
collection DOAJ
description Purpose. To compare the functional and clinical outcomes of the iris-claw intraocular lens (IOL) placed on the anterior versus posterior surface of the iris. Patients and Methods. A multicenter, retrospective study. Data on eyes that underwent anterior or retropupillary iris-claw IOL implantation because of inadequate capsular support secondary to complicated cataract surgery, trauma, and dislocated/opacified IOLs since January 2015 were analyzed. For study inclusion, evaluation results had to be available in the medical records both preoperatively and at 1 and 12 months after implantation. The following parameters were compared between the groups: best-corrected distance visual acuity (BCDVA), spherical and cylindrical refractive error, endothelial cell density (ECD), central macular thickness (CMT), and percentage and type of postoperative complications. Results. In total, 60 eyes of 60 patients aged 73 ± 13 years were included: 28 eyes (47%) involved anterior, and 32 eyes (53%) retropupillary, iris-claw IOL fixations. Preoperatively, the groups were similar in all parameters except for a significantly higher proportion of retropupillary fixations in patients who had previously experienced a closed-globe trauma (p=0.03). The groups showed comparable improvements in BCDVA after surgery (final BCDVA: 0.34 ± 0.45 vs. 0.37 ± 0.50 logMAR in the anterior and retropupillary placement groups, respectively). During follow-up, no group difference was observed in refractive error or CMT. Both groups experienced similarly marked ECD loss and showed similar incidence of postoperative complications, with cystoid macular edema being the most common complication. Multivariable linear regression showed that BCDVA at 1 month was the best predictor of the final BCDVA. Conclusions. Anterior chamber and posterior chamber iris-claw IOL fixations proved equally effective and safe for aphakic correction in eyes with inadequate capsular support.
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spelling doaj-art-b6ee1961255a4fefaf23ef07a9150d6f2025-02-03T01:11:42ZengWileyJournal of Ophthalmology2090-004X2090-00582018-01-01201810.1155/2018/84635698463569Comparative Analysis of the Safety and Functional Outcomes of Anterior versus Retropupillary Iris-Claw IOL FixationPaolo Mora0Giacomo Calzetti1Stefania Favilla2Matteo Forlini3Salvatore Tedesco4Purva Date5Viola Tagliavini6Arturo Carta7Rino Frisina8Emilio Pedrotti9Stefano Gandolfi10Ophthalmology Unit, University Hospital of Parma, Parma, ItalyOphthalmology Unit, University Hospital of Parma, Parma, ItalyIndependent Researcher, Parma, ItalyOphthalmology Unit, University Hospital of Parma, Parma, ItalyOphthalmology Unit, University Hospital of Parma, Parma, ItalyAditya Jyot Eye Hospital, Wadala, Mumbai, IndiaOphthalmology Unit, University Hospital of Parma, Parma, ItalyOphthalmology Unit, University Hospital of Parma, Parma, ItalyDepartment of Ophthalmology, University of Padova, Padova, ItalyEye Clinic, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, AOUI-Policlinico G. B. Rossi, Verona, ItalyOphthalmology Unit, University Hospital of Parma, Parma, ItalyPurpose. To compare the functional and clinical outcomes of the iris-claw intraocular lens (IOL) placed on the anterior versus posterior surface of the iris. Patients and Methods. A multicenter, retrospective study. Data on eyes that underwent anterior or retropupillary iris-claw IOL implantation because of inadequate capsular support secondary to complicated cataract surgery, trauma, and dislocated/opacified IOLs since January 2015 were analyzed. For study inclusion, evaluation results had to be available in the medical records both preoperatively and at 1 and 12 months after implantation. The following parameters were compared between the groups: best-corrected distance visual acuity (BCDVA), spherical and cylindrical refractive error, endothelial cell density (ECD), central macular thickness (CMT), and percentage and type of postoperative complications. Results. In total, 60 eyes of 60 patients aged 73 ± 13 years were included: 28 eyes (47%) involved anterior, and 32 eyes (53%) retropupillary, iris-claw IOL fixations. Preoperatively, the groups were similar in all parameters except for a significantly higher proportion of retropupillary fixations in patients who had previously experienced a closed-globe trauma (p=0.03). The groups showed comparable improvements in BCDVA after surgery (final BCDVA: 0.34 ± 0.45 vs. 0.37 ± 0.50 logMAR in the anterior and retropupillary placement groups, respectively). During follow-up, no group difference was observed in refractive error or CMT. Both groups experienced similarly marked ECD loss and showed similar incidence of postoperative complications, with cystoid macular edema being the most common complication. Multivariable linear regression showed that BCDVA at 1 month was the best predictor of the final BCDVA. Conclusions. Anterior chamber and posterior chamber iris-claw IOL fixations proved equally effective and safe for aphakic correction in eyes with inadequate capsular support.http://dx.doi.org/10.1155/2018/8463569
spellingShingle Paolo Mora
Giacomo Calzetti
Stefania Favilla
Matteo Forlini
Salvatore Tedesco
Purva Date
Viola Tagliavini
Arturo Carta
Rino Frisina
Emilio Pedrotti
Stefano Gandolfi
Comparative Analysis of the Safety and Functional Outcomes of Anterior versus Retropupillary Iris-Claw IOL Fixation
Journal of Ophthalmology
title Comparative Analysis of the Safety and Functional Outcomes of Anterior versus Retropupillary Iris-Claw IOL Fixation
title_full Comparative Analysis of the Safety and Functional Outcomes of Anterior versus Retropupillary Iris-Claw IOL Fixation
title_fullStr Comparative Analysis of the Safety and Functional Outcomes of Anterior versus Retropupillary Iris-Claw IOL Fixation
title_full_unstemmed Comparative Analysis of the Safety and Functional Outcomes of Anterior versus Retropupillary Iris-Claw IOL Fixation
title_short Comparative Analysis of the Safety and Functional Outcomes of Anterior versus Retropupillary Iris-Claw IOL Fixation
title_sort comparative analysis of the safety and functional outcomes of anterior versus retropupillary iris claw iol fixation
url http://dx.doi.org/10.1155/2018/8463569
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