Mitochondrial calcium uniporter is required for thermogenic adaptation mediated by reactive oxygen species signaling

Mitochondrial Ca2+ influx via mitochondrial calcium uniporter (MCU) accelerates mitochondrial biogenesis and energy metabolism. Nevertheless, the molecular mechanism of MCU-dependent mitochondrial activation and thermogenesis in thermogenic adipose tissues remains elusive. In this study, we demonstr...

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Bibliographic Details
Main Authors: Suji Kim, Seung-Kuy Cha, Kyu-Sang Park, Jun Namkung
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Journal of Lipid Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S002222752500094X
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