Development and Evaluation of the Immunogenic Potential of an Unmodified Nucleoside mRNA Vaccine for Herpes Zoster

Background/Objectives: Approved mRNA vaccines commonly use sequences modified with pseudouridine to enhance translation efficiency and mRNA stability. However, this modification can result in ribosomal frameshifts, reduced immunogenicity, and higher production costs. This study aimed to explore the...

Full description

Saved in:
Bibliographic Details
Main Authors: Shun Zhang, Xiaojie Wang, Tongyi Zhao, Chen Yang, Lulu Huang
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/13/1/68
Tags: Add Tag
No Tags, Be the first to tag this record!