Synergistic Anticancer Effects of Bleomycin and Hesperidin Combination on A549 Non-Small Cell Lung Cancer Cells: Antiproliferative, Apoptotic, Anti-Angiogenic, and Autophagic Insights

Synergistic Anticancer Effects of Bleomycin and Hesperidin Combination on A549 Non-Small Cell Lung Cancer Cells: Antiproliferative, Apoptotic, Anti-Angiogenic, and Autophagic Insights

<b>Background</b>: This study investigated the combined effects of hesperidin (Hesp), a natural flavonoid, with bleomycin (BL), a commonly used chemotherapy agent, on A549 human lung cancer cells. <b>Methods</b>: Key parameters assessed included cell viability, colony formati...

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Bibliographic Details
Main Authors: Mehmet Kadir Erdogan, Guleser Ozer
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Pharmaceuticals
Subjects:
lung cancer
bleomycin
hesperidin
apoptosis
autophagy
angiogenesis
Online Access:https://www.mdpi.com/1424-8247/18/2/254
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https://www.mdpi.com/1424-8247/18/2/254

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