DeepDeconUQ estimates malignant cell fraction prediction intervals in bulk RNA-seq tissue.

Accurate estimation of malignant cell fractions in tissues plays a critical role in cancer diagnosis, prognosis, and subsequent treatment decisions. However, most currently available methods provide only point estimates, neglecting the quantification of uncertainties, which is essential for both cli...

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Bibliographic Details
Main Authors: Jiawei Huang, Yuxuan Du, Kevin R Kelly, Jinchi Lv, Yingying Fan, Jiang F Zhong, Fengzhu Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-06-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1013133
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