Engineering fibroblast with reprogramming and spheronization for bone defect repair

Engineering fibroblast with reprogramming and spheronization for bone defect repair

Bone diseases profoundly affect patients, particularly the elderly, leading to severe health complications and disabilities. Osteoblasts play a crucial role in bone formation and are ideal candidates for treating bone diseases and engineering living materials. However, the stem and progenitor cells...

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Bibliographic Details
Main Authors: Yanjiao Li, Bin Jiang, Zhen Wu, Zhaoxia Ma, Lihua Qiu, Wen Cui, Yunhui Zhao, Jinghe Yan, Daiping Ma, Xingfei Wu, Shu Liang, Sitao Wang, Yanqun Zhao, Mengting Wang, Min Hu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-08-01
Series:Bioactive Materials
Subjects:
Engineering fibroblast
Elderly autologous induced osteoblast
Spheroid
Endogenous revascularization and osteogenesis
High productivity and survival
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X25001677
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