Impact of maternal microplastic exposure on offspring lung structure and function: Insights into transcriptional misregulation and the TGF-β/α-SMA pathway

Impact of maternal microplastic exposure on offspring lung structure and function: Insights into transcriptional misregulation and the TGF-β/α-SMA pathway

The “Developmental Origins of Health and Disease” (DOHaD) theory suggests that prenatal exposure to harmful environmental factors may impair fetal tissue development, increasing the risk of diseases later in life. This study investigated the effects of prenatal exposure to polystyrene microplastics...

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Main Authors: Hong-Ren Yu, Mao-Meng Tiao, Shun-Chen Huang, Jim Jinn-Chyuan Sheu, You-Lin Tain, Jiunn-Ming Sheen, I.-Chun Lin, Ching-Chou Tsai, Li-Tung Huang, Chien-Ning Hsu, Chih-Min Tsai, Yu-Hsiu Lin, Pei-Fen Lee, Yu-Tsun Su
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Ecotoxicology and Environmental Safety
Subjects:
DOHaD
prenatal
microplastics
lung
tight junction
transcription
Online Access:http://www.sciencedirect.com/science/article/pii/S014765132500733X
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