Evaluating the relationship between caregiver depression, social support, and children’s internalizing and externalizing symptoms in families affected by 22q11.2 deletion syndrome

Evaluating the relationship between caregiver depression, social support, and children’s internalizing and externalizing symptoms in families affected by 22q11.2 deletion syndrome

Abstract Background 22q11.2 Deletion Syndrome (22q11DS) is the most common microdeletion syndrome. It exhibits broad phenotypic variability, often including conditions like autism spectrum disorder and intellectual disability. Caregivers of children with 22q11DS are known to be at increased risk of...

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Main Authors: Holly Carbyn, Abiaz Hossain, Raquel L. Dias, Lisa D. Palmer, Sophie Ayoub, Patricia Lingley-Pottie, Patrick J. McGrath, Andrea L. Rideout, Andrea Shugar, Cheryl Cytrynbaum, Donna M. McDonald-McGinn, Ann Swillen, Anne S. Bassett, Sandra Meier
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Orphanet Journal of Rare Diseases
Subjects:
22q11.2 deletion syndrome
Mental health
Depression
Social support
Mediation
Online Access:https://doi.org/10.1186/s13023-025-03955-2
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https://doi.org/10.1186/s13023-025-03955-2

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