Effects of Hydrofluoroalkane and Dry Powder-Formulated Corticosteroids on Sputum Inflammatory Markers in Asthmatic Patients
BACKGROUND: Inhaled corticosteroids are powerful drugs that can suppress airway inflammation in asthmatic patients. Deposition of most of the inhaled corticosteroid occurs mainly in the central airways. However, a new hydrofluoroalkane formulation of beclomethasone dipropionate (HFA-BDP) is preferen...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2006-01-01
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| Series: | Canadian Respiratory Journal |
| Online Access: | http://dx.doi.org/10.1155/2006/648392 |
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| _version_ | 1832567823546712064 |
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| author | Hans-Peter Hauber Rame Taha Celine Bergeron Vladimir Migounov Qutayba Hamid Ron Olivenstein |
| author_facet | Hans-Peter Hauber Rame Taha Celine Bergeron Vladimir Migounov Qutayba Hamid Ron Olivenstein |
| author_sort | Hans-Peter Hauber |
| collection | DOAJ |
| description | BACKGROUND: Inhaled corticosteroids are powerful drugs that can suppress airway inflammation in asthmatic patients. Deposition of most of the inhaled corticosteroid occurs mainly in the central airways. However, a new hydrofluoroalkane formulation of beclomethasone dipropionate (HFA-BDP) is preferentially deposited in the distal airways. Inflammatory characteristics of induced sputum have been shown to differ in samples collected early after sputum induction compared with later. |
| format | Article |
| id | doaj-art-b5ea5054e24749d3a110831a7ec1d356 |
| institution | Kabale University |
| issn | 1198-2241 |
| language | English |
| publishDate | 2006-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Respiratory Journal |
| spelling | doaj-art-b5ea5054e24749d3a110831a7ec1d3562025-02-03T01:00:34ZengWileyCanadian Respiratory Journal1198-22412006-01-01132737810.1155/2006/648392Effects of Hydrofluoroalkane and Dry Powder-Formulated Corticosteroids on Sputum Inflammatory Markers in Asthmatic PatientsHans-Peter Hauber0Rame Taha1Celine Bergeron2Vladimir Migounov3Qutayba Hamid4Ron Olivenstein5Meakins-Christie Laboratories, McGill University, Montreal, Quebec, CanadaMeakins-Christie Laboratories, McGill University, Montreal, Quebec, CanadaMeakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada3M Pharmaceuticals, London, Ontario, CanadaMeakins-Christie Laboratories, McGill University, Montreal, Quebec, CanadaMontreal Chest Institute, Montreal, Quebec, CanadaBACKGROUND: Inhaled corticosteroids are powerful drugs that can suppress airway inflammation in asthmatic patients. Deposition of most of the inhaled corticosteroid occurs mainly in the central airways. However, a new hydrofluoroalkane formulation of beclomethasone dipropionate (HFA-BDP) is preferentially deposited in the distal airways. Inflammatory characteristics of induced sputum have been shown to differ in samples collected early after sputum induction compared with later.http://dx.doi.org/10.1155/2006/648392 |
| spellingShingle | Hans-Peter Hauber Rame Taha Celine Bergeron Vladimir Migounov Qutayba Hamid Ron Olivenstein Effects of Hydrofluoroalkane and Dry Powder-Formulated Corticosteroids on Sputum Inflammatory Markers in Asthmatic Patients Canadian Respiratory Journal |
| title | Effects of Hydrofluoroalkane and Dry Powder-Formulated Corticosteroids on Sputum Inflammatory Markers in Asthmatic Patients |
| title_full | Effects of Hydrofluoroalkane and Dry Powder-Formulated Corticosteroids on Sputum Inflammatory Markers in Asthmatic Patients |
| title_fullStr | Effects of Hydrofluoroalkane and Dry Powder-Formulated Corticosteroids on Sputum Inflammatory Markers in Asthmatic Patients |
| title_full_unstemmed | Effects of Hydrofluoroalkane and Dry Powder-Formulated Corticosteroids on Sputum Inflammatory Markers in Asthmatic Patients |
| title_short | Effects of Hydrofluoroalkane and Dry Powder-Formulated Corticosteroids on Sputum Inflammatory Markers in Asthmatic Patients |
| title_sort | effects of hydrofluoroalkane and dry powder formulated corticosteroids on sputum inflammatory markers in asthmatic patients |
| url | http://dx.doi.org/10.1155/2006/648392 |
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