Behaviour of the Foramen Ovale Flow in Fetuses with Intrauterine Growth Restriction
Background. Foramen ovale (FO) flow may be altered in IUGR. This study was designed to test this hypothesis. Methods. Forty pregnant women (24–38 weeks) were divided into 3 groups: group I (IUGR), group II (adequate growth and maternal hypertension), and group III (normal controls). Impedance across...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Obstetrics and Gynecology International |
| Online Access: | http://dx.doi.org/10.1155/2018/1496903 |
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| author | Ângela R. L. Nader Paulo Zielinsky Alexandre Antonio Naujorks Luiz Henrique S. Nicoloso Antonio Luiz Piccoli Junior Natássia Miranda Sulis Luiza Ferreira van der Sand Victoria de Bittencourt Antunes Gabriela dos Santos Marinho Fernanda Greinert dos Santos Natan Pereira Gosmann Eduardo Becker Júnior Renato Frajndlich Tamara Beherens Marcelo Brandão da Silva Caroline Barbisan Stefano Busato Mauro Lopes Caroline Klein |
| author_facet | Ângela R. L. Nader Paulo Zielinsky Alexandre Antonio Naujorks Luiz Henrique S. Nicoloso Antonio Luiz Piccoli Junior Natássia Miranda Sulis Luiza Ferreira van der Sand Victoria de Bittencourt Antunes Gabriela dos Santos Marinho Fernanda Greinert dos Santos Natan Pereira Gosmann Eduardo Becker Júnior Renato Frajndlich Tamara Beherens Marcelo Brandão da Silva Caroline Barbisan Stefano Busato Mauro Lopes Caroline Klein |
| author_sort | Ângela R. L. Nader |
| collection | DOAJ |
| description | Background. Foramen ovale (FO) flow may be altered in IUGR. This study was designed to test this hypothesis. Methods. Forty pregnant women (24–38 weeks) were divided into 3 groups: group I (IUGR), group II (adequate growth and maternal hypertension), and group III (normal controls). Impedance across the FO was assessed by the FO pulsatility index (FOPI): (systolic velocity − presystolic velocity)/mean velocity. Statistical analysis utilized ANOVA, Tukey test, and ROC curves. Results. Mean FOPI in IUGR fetuses (n = 15) was 3.70 ± 0.99 (3.15–4.26); in the group II (n = 12), it was 2.84 ± 0.69 (2.40–3.28), and in the group III (n = 13), it was 2.77 ± 0.44 (2.50–3.04) (p=0.004). FOPI and UtA RI were correlated (r = 0.375, p=0.017), as well as FOPI and UA RI (r = 0.356, p=0.024) and, inversely, FOPI and MCA RI (r = −0.359, p=0.023). Conclusions. The FO flow pulsatility index is increased in fetuses with IUGR, probably as a result of impaired left ventricular diastolic function. |
| format | Article |
| id | doaj-art-b5d4597a1ca0453ca88c15cb3998f0b4 |
| institution | Kabale University |
| issn | 1687-9589 1687-9597 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Obstetrics and Gynecology International |
| spelling | doaj-art-b5d4597a1ca0453ca88c15cb3998f0b42025-02-03T01:00:36ZengWileyObstetrics and Gynecology International1687-95891687-95972018-01-01201810.1155/2018/14969031496903Behaviour of the Foramen Ovale Flow in Fetuses with Intrauterine Growth RestrictionÂngela R. L. Nader0Paulo Zielinsky1Alexandre Antonio Naujorks2Luiz Henrique S. Nicoloso3Antonio Luiz Piccoli Junior4Natássia Miranda Sulis5Luiza Ferreira van der Sand6Victoria de Bittencourt Antunes7Gabriela dos Santos Marinho8Fernanda Greinert dos Santos9Natan Pereira Gosmann10Eduardo Becker Júnior11Renato Frajndlich12Tamara Beherens13Marcelo Brandão da Silva14Caroline Barbisan15Stefano Busato16Mauro Lopes17Caroline Klein18Unidade de Cardiologia Fetal, Instituto de Cardiologia do Rio Grande do Sul, Porto Alegre, RS, BrazilUnidade de Cardiologia Fetal, Instituto de Cardiologia do Rio Grande do Sul, Porto Alegre, RS, BrazilUnidade de Cardiologia Fetal, Instituto de Cardiologia do Rio Grande do Sul, Porto Alegre, RS, BrazilUnidade de Cardiologia Fetal, Instituto de Cardiologia do Rio Grande do Sul, Porto Alegre, RS, BrazilUnidade de Cardiologia Fetal, Instituto de Cardiologia do Rio Grande do Sul, Porto Alegre, RS, BrazilUnidade de Cardiologia Fetal, Instituto de Cardiologia do Rio Grande do Sul, Porto Alegre, RS, BrazilUnidade de Cardiologia Fetal, Instituto de Cardiologia do Rio Grande do Sul, Porto Alegre, RS, BrazilUnidade de Cardiologia Fetal, Instituto de Cardiologia do Rio Grande do Sul, Porto Alegre, RS, BrazilUnidade de Cardiologia Fetal, Instituto de Cardiologia do Rio Grande do Sul, Porto Alegre, RS, BrazilUnidade de Cardiologia Fetal, Instituto de Cardiologia do Rio Grande do Sul, Porto Alegre, RS, BrazilHospital de Clinicas de Porto Alegre, Porto Alegre, RS, BrazilUnidade de Cardiologia Fetal, Instituto de Cardiologia do Rio Grande do Sul, Porto Alegre, RS, BrazilUnidade de Cardiologia Fetal, Instituto de Cardiologia do Rio Grande do Sul, Porto Alegre, RS, BrazilUnidade de Cardiologia Fetal, Instituto de Cardiologia do Rio Grande do Sul, Porto Alegre, RS, BrazilUnidade de Cardiologia Fetal, Instituto de Cardiologia do Rio Grande do Sul, Porto Alegre, RS, BrazilUnidade de Cardiologia Fetal, Instituto de Cardiologia do Rio Grande do Sul, Porto Alegre, RS, BrazilUnidade de Cardiologia Fetal, Instituto de Cardiologia do Rio Grande do Sul, Porto Alegre, RS, BrazilUnidade de Cardiologia Fetal, Instituto de Cardiologia do Rio Grande do Sul, Porto Alegre, RS, BrazilUnidade de Cardiologia Fetal, Instituto de Cardiologia do Rio Grande do Sul, Porto Alegre, RS, BrazilBackground. Foramen ovale (FO) flow may be altered in IUGR. This study was designed to test this hypothesis. Methods. Forty pregnant women (24–38 weeks) were divided into 3 groups: group I (IUGR), group II (adequate growth and maternal hypertension), and group III (normal controls). Impedance across the FO was assessed by the FO pulsatility index (FOPI): (systolic velocity − presystolic velocity)/mean velocity. Statistical analysis utilized ANOVA, Tukey test, and ROC curves. Results. Mean FOPI in IUGR fetuses (n = 15) was 3.70 ± 0.99 (3.15–4.26); in the group II (n = 12), it was 2.84 ± 0.69 (2.40–3.28), and in the group III (n = 13), it was 2.77 ± 0.44 (2.50–3.04) (p=0.004). FOPI and UtA RI were correlated (r = 0.375, p=0.017), as well as FOPI and UA RI (r = 0.356, p=0.024) and, inversely, FOPI and MCA RI (r = −0.359, p=0.023). Conclusions. The FO flow pulsatility index is increased in fetuses with IUGR, probably as a result of impaired left ventricular diastolic function.http://dx.doi.org/10.1155/2018/1496903 |
| spellingShingle | Ângela R. L. Nader Paulo Zielinsky Alexandre Antonio Naujorks Luiz Henrique S. Nicoloso Antonio Luiz Piccoli Junior Natássia Miranda Sulis Luiza Ferreira van der Sand Victoria de Bittencourt Antunes Gabriela dos Santos Marinho Fernanda Greinert dos Santos Natan Pereira Gosmann Eduardo Becker Júnior Renato Frajndlich Tamara Beherens Marcelo Brandão da Silva Caroline Barbisan Stefano Busato Mauro Lopes Caroline Klein Behaviour of the Foramen Ovale Flow in Fetuses with Intrauterine Growth Restriction Obstetrics and Gynecology International |
| title | Behaviour of the Foramen Ovale Flow in Fetuses with Intrauterine Growth Restriction |
| title_full | Behaviour of the Foramen Ovale Flow in Fetuses with Intrauterine Growth Restriction |
| title_fullStr | Behaviour of the Foramen Ovale Flow in Fetuses with Intrauterine Growth Restriction |
| title_full_unstemmed | Behaviour of the Foramen Ovale Flow in Fetuses with Intrauterine Growth Restriction |
| title_short | Behaviour of the Foramen Ovale Flow in Fetuses with Intrauterine Growth Restriction |
| title_sort | behaviour of the foramen ovale flow in fetuses with intrauterine growth restriction |
| url | http://dx.doi.org/10.1155/2018/1496903 |
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