Aging restricts the initial neural patterning potential of developing neural stem and progenitor cells in the adult brain

Aging restricts the initial neural patterning potential of developing neural stem and progenitor cells in the adult brain

IntroductionNeurosphere culture is widely used to expand neural stem and progenitor cells (NSPCs) of the nervous system. Understanding the identity of NSPCs, such as the principals involved in spatiotemporal patterning, will improve our chances of using NSPCs for neurodevelopmental and brain repair...

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Bibliographic Details
Main Authors: Saeideh Aran, Mohammad Ghasem Golmohammadi, Mohsen Sagha, Kamran Ghaedi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Aging Neuroscience
Subjects:
adult brain
aging
ganglionic eminence
neural patterning
neural stem and progenitor cell
neurosphere
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2024.1498308/full
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