Cutaneous Human Papillomavirus E7 Type-Specific Effects on Differentiation and Proliferation of Organotypic Skin Cultures
Background: A role for cutaneous human β-papillomavirus (HPV) types as co-factors in the development of non-melanoma skin cancer has been postulated. Here we have investigated the effects of E7 expression on keratinocyte differentiation, proliferation and cell-cycle proteins in organotypic skin cult...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2009-01-01
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| Series: | Cellular Oncology |
| Online Access: | http://dx.doi.org/10.3233/CLO-2009-0476 |
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| _version_ | 1832560339981434880 |
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| author | K. Westphal B. Akgül A. Storey I. Nindl |
| author_facet | K. Westphal B. Akgül A. Storey I. Nindl |
| author_sort | K. Westphal |
| collection | DOAJ |
| description | Background: A role for cutaneous human β-papillomavirus (HPV) types as co-factors in the development of non-melanoma skin cancer has been postulated. Here we have investigated the effects of E7 expression on keratinocyte differentiation, proliferation and cell-cycle proteins in organotypic skin cultures. |
| format | Article |
| id | doaj-art-b51fb761d6234d399ba30eaf752a4a9d |
| institution | Kabale University |
| issn | 1570-5870 1875-8606 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cellular Oncology |
| spelling | doaj-art-b51fb761d6234d399ba30eaf752a4a9d2025-02-03T01:27:49ZengWileyCellular Oncology1570-58701875-86062009-01-0131321322610.3233/CLO-2009-0476Cutaneous Human Papillomavirus E7 Type-Specific Effects on Differentiation and Proliferation of Organotypic Skin CulturesK. Westphal0B. Akgül1A. Storey2I. Nindl3Department of Dermatology, Venereology and Allergy, Charité, Skin Cancer Center Charité, University Hospital of Berlin, Berlin, GermanyCancer Research UK, Skin Tumour Laboratory, ICMS, London, UKCancer Research UK, Skin Tumour Laboratory, ICMS, London, UKDepartment of Dermatology, Venereology and Allergy, Charité, Skin Cancer Center Charité, University Hospital of Berlin, Berlin, GermanyBackground: A role for cutaneous human β-papillomavirus (HPV) types as co-factors in the development of non-melanoma skin cancer has been postulated. Here we have investigated the effects of E7 expression on keratinocyte differentiation, proliferation and cell-cycle proteins in organotypic skin cultures.http://dx.doi.org/10.3233/CLO-2009-0476 |
| spellingShingle | K. Westphal B. Akgül A. Storey I. Nindl Cutaneous Human Papillomavirus E7 Type-Specific Effects on Differentiation and Proliferation of Organotypic Skin Cultures Cellular Oncology |
| title | Cutaneous Human Papillomavirus E7 Type-Specific Effects on Differentiation and Proliferation of Organotypic Skin Cultures |
| title_full | Cutaneous Human Papillomavirus E7 Type-Specific Effects on Differentiation and Proliferation of Organotypic Skin Cultures |
| title_fullStr | Cutaneous Human Papillomavirus E7 Type-Specific Effects on Differentiation and Proliferation of Organotypic Skin Cultures |
| title_full_unstemmed | Cutaneous Human Papillomavirus E7 Type-Specific Effects on Differentiation and Proliferation of Organotypic Skin Cultures |
| title_short | Cutaneous Human Papillomavirus E7 Type-Specific Effects on Differentiation and Proliferation of Organotypic Skin Cultures |
| title_sort | cutaneous human papillomavirus e7 type specific effects on differentiation and proliferation of organotypic skin cultures |
| url | http://dx.doi.org/10.3233/CLO-2009-0476 |
| work_keys_str_mv | AT kwestphal cutaneoushumanpapillomaviruse7typespecificeffectsondifferentiationandproliferationoforganotypicskincultures AT bakgul cutaneoushumanpapillomaviruse7typespecificeffectsondifferentiationandproliferationoforganotypicskincultures AT astorey cutaneoushumanpapillomaviruse7typespecificeffectsondifferentiationandproliferationoforganotypicskincultures AT inindl cutaneoushumanpapillomaviruse7typespecificeffectsondifferentiationandproliferationoforganotypicskincultures |