CEACAM5 exacerbates asthma by inducing ferroptosis and autophagy in airway epithelial cells through the JAK/STAT6-dependent pathway

CEACAM5 exacerbates asthma by inducing ferroptosis and autophagy in airway epithelial cells through the JAK/STAT6-dependent pathway

Objectives Asthma, a prevalent chronic disease, poses significant health threats and burdens healthcare systems. This study focused on the role of bronchial epithelial cells in asthma pathophysiology.Methods Bioinformatics was used to identify key asthmarelated genes. An ovalbumin-sensitized mouse m...

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Bibliographic Details
Main Authors: Si Liu, Li Chen, Yunxiao Shang
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Redox Report
Subjects:
Bronchial epithelial cells
CEACAM5
ferroptosis
autophagy
JAK
STAT6
Online Access:https://www.tandfonline.com/doi/10.1080/13510002.2024.2444755
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https://www.tandfonline.com/doi/10.1080/13510002.2024.2444755

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