The global stability of an SIRS model with infection age

Infection age is an important factor affecting the transmission ofinfectious diseases. In this paper, we consider an SIRS modelwith infection age, which is described by a mixed system ofordinary differential equations and partial differentialequations. The expression of the basic reproduction numbe...

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Main Authors: Yuming Chen, Junyuan Yang, Fengqin Zhang
Format: Article
Language:English
Published: AIMS Press 2013-12-01
Series:Mathematical Biosciences and Engineering
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Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2014.11.449
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author Yuming Chen
Junyuan Yang
Fengqin Zhang
author_facet Yuming Chen
Junyuan Yang
Fengqin Zhang
author_sort Yuming Chen
collection DOAJ
description Infection age is an important factor affecting the transmission ofinfectious diseases. In this paper, we consider an SIRS modelwith infection age, which is described by a mixed system ofordinary differential equations and partial differentialequations. The expression of the basic reproduction number$\mathscr {R}_0$ is obtained. If $\mathscr{R}_0\le 1$ then themodel only has the disease-free equilibrium, while if$\mathscr{R}_0>1$ then besides the disease-free equilibrium themodel also has an endemic equilibrium. Moreover, if$\mathscr{R}_0<1 then="" the="" disease-free="" equilibrium="" is="" globally="" asymptotically="" stable="" otherwise="" it="" is="" unstable="" if="" mathscr="" r="" _0="">1$ then the endemicequilibrium is globally asymptotically stable under additional conditions. The local stabilityis established through linearization. The global stability of thedisease-free equilibrium is shown by applying the fluctuationlemma and that of the endemic equilibrium is proved by employing Lyapunov functionals. The theoretical results are illustrated with numerical simulations.
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spelling doaj-art-b4b35ef14ee6477bb5e1e06fff9f69542025-01-24T02:28:12ZengAIMS PressMathematical Biosciences and Engineering1551-00182013-12-0111344946910.3934/mbe.2014.11.449The global stability of an SIRS model with infection ageYuming Chen0Junyuan Yang1Fengqin Zhang2Department of Applied Mathematics, Yuncheng University, Yuncheng 044000, ShanxiDepartment of Applied Mathematics, Yuncheng University, Yuncheng 044000, ShanxiDepartment of Applied Mathematics, Yuncheng University, Yuncheng 044000, ShanxiInfection age is an important factor affecting the transmission ofinfectious diseases. In this paper, we consider an SIRS modelwith infection age, which is described by a mixed system ofordinary differential equations and partial differentialequations. The expression of the basic reproduction number$\mathscr {R}_0$ is obtained. If $\mathscr{R}_0\le 1$ then themodel only has the disease-free equilibrium, while if$\mathscr{R}_0>1$ then besides the disease-free equilibrium themodel also has an endemic equilibrium. Moreover, if$\mathscr{R}_0<1 then="" the="" disease-free="" equilibrium="" is="" globally="" asymptotically="" stable="" otherwise="" it="" is="" unstable="" if="" mathscr="" r="" _0="">1$ then the endemicequilibrium is globally asymptotically stable under additional conditions. The local stabilityis established through linearization. The global stability of thedisease-free equilibrium is shown by applying the fluctuationlemma and that of the endemic equilibrium is proved by employing Lyapunov functionals. The theoretical results are illustrated with numerical simulations.https://www.aimspress.com/article/doi/10.3934/mbe.2014.11.449global stabilitypersistence.sirs modelinfection age
spellingShingle Yuming Chen
Junyuan Yang
Fengqin Zhang
The global stability of an SIRS model with infection age
Mathematical Biosciences and Engineering
global stability
persistence.
sirs model
infection age
title The global stability of an SIRS model with infection age
title_full The global stability of an SIRS model with infection age
title_fullStr The global stability of an SIRS model with infection age
title_full_unstemmed The global stability of an SIRS model with infection age
title_short The global stability of an SIRS model with infection age
title_sort global stability of an sirs model with infection age
topic global stability
persistence.
sirs model
infection age
url https://www.aimspress.com/article/doi/10.3934/mbe.2014.11.449
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