Development of Integrated Actinide Chemistry Application, AACE, for Acceleration of Actinide Chemistry Experiments
Efficient separation of Minor Actinide (MA) from High-Level Liquid Waste (HLLW) is essential in next generation reprocessing systems. To enable this, finding an efficient separation system is inevitable. We employ a chemoinformatic approach to find suitable diluents, particularly fluorinated diluent...
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| Format: | Article |
| Language: | English |
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EDP Sciences
2025-01-01
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| Series: | EPJ Web of Conferences |
| Online Access: | https://www.epj-conferences.org/articles/epjconf/pdf/2025/02/epjconf_atalante2025_01007.pdf |
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| author | Nakase Masahiko Nishihara Takahiro Ikhwan Fauzia Hanum Okamura Tomohiro Matsui Kota |
| author_facet | Nakase Masahiko Nishihara Takahiro Ikhwan Fauzia Hanum Okamura Tomohiro Matsui Kota |
| author_sort | Nakase Masahiko |
| collection | DOAJ |
| description | Efficient separation of Minor Actinide (MA) from High-Level Liquid Waste (HLLW) is essential in next generation reprocessing systems. To enable this, finding an efficient separation system is inevitable. We employ a chemoinformatic approach to find suitable diluents, particularly fluorinated diluents, due to some advantages. To efficiently find the candidate molecules we developed Acceleration of Actinide Chemistry Experiment (AACE), which can deploy transfer learning (TL) and human-in-the-loop machine learning (HITL-ML). Our approach utilizes Hansen’s solubility parameters derived from molecular structures to predict solubility and extractability, create extraction models for MA surrogate Lanthanide (Ln) and MA. This manuscript outlines the methodology for diluent exploration and the function of AACE. |
| format | Article |
| id | doaj-art-b49a87554570434ea28c7e011ed0a115 |
| institution | Kabale University |
| issn | 2100-014X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | EPJ Web of Conferences |
| spelling | doaj-art-b49a87554570434ea28c7e011ed0a1152025-02-05T10:53:04ZengEDP SciencesEPJ Web of Conferences2100-014X2025-01-013170100710.1051/epjconf/202531701007epjconf_atalante2025_01007Development of Integrated Actinide Chemistry Application, AACE, for Acceleration of Actinide Chemistry ExperimentsNakase Masahiko0Nishihara Takahiro1Ikhwan Fauzia Hanum2Okamura Tomohiro3Matsui Kota4Tokyo Institute of Technology, Institute of Innovative Research, laboratory for Zero-Carbon EnergyTokyo Institute of Technology, Institute of Innovative Research, laboratory for Zero-Carbon EnergyTokyo Institute of Technology, Institute of Innovative Research, laboratory for Zero-Carbon EnergyTokyo Institute of Technology, Institute of Innovative Research, laboratory for Zero-Carbon EnergyNagoya University Graduate School of Medicine, Department of BiostatisticsEfficient separation of Minor Actinide (MA) from High-Level Liquid Waste (HLLW) is essential in next generation reprocessing systems. To enable this, finding an efficient separation system is inevitable. We employ a chemoinformatic approach to find suitable diluents, particularly fluorinated diluents, due to some advantages. To efficiently find the candidate molecules we developed Acceleration of Actinide Chemistry Experiment (AACE), which can deploy transfer learning (TL) and human-in-the-loop machine learning (HITL-ML). Our approach utilizes Hansen’s solubility parameters derived from molecular structures to predict solubility and extractability, create extraction models for MA surrogate Lanthanide (Ln) and MA. This manuscript outlines the methodology for diluent exploration and the function of AACE.https://www.epj-conferences.org/articles/epjconf/pdf/2025/02/epjconf_atalante2025_01007.pdf |
| spellingShingle | Nakase Masahiko Nishihara Takahiro Ikhwan Fauzia Hanum Okamura Tomohiro Matsui Kota Development of Integrated Actinide Chemistry Application, AACE, for Acceleration of Actinide Chemistry Experiments EPJ Web of Conferences |
| title | Development of Integrated Actinide Chemistry Application, AACE, for Acceleration of Actinide Chemistry Experiments |
| title_full | Development of Integrated Actinide Chemistry Application, AACE, for Acceleration of Actinide Chemistry Experiments |
| title_fullStr | Development of Integrated Actinide Chemistry Application, AACE, for Acceleration of Actinide Chemistry Experiments |
| title_full_unstemmed | Development of Integrated Actinide Chemistry Application, AACE, for Acceleration of Actinide Chemistry Experiments |
| title_short | Development of Integrated Actinide Chemistry Application, AACE, for Acceleration of Actinide Chemistry Experiments |
| title_sort | development of integrated actinide chemistry application aace for acceleration of actinide chemistry experiments |
| url | https://www.epj-conferences.org/articles/epjconf/pdf/2025/02/epjconf_atalante2025_01007.pdf |
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