Low Citrate Synthase Activity Is Associated with Glucose Intolerance and Lipotoxicity
Citrate synthase (CS) is a key mitochondrial enzyme. The aim of this study was to test the hypothesis that low CS activity impairs the metabolic health of mice fed a high fat diet (HFD) and promotes palmitate-induced lipotoxicity in muscle cells. C57BL/6J (B6) mice and congenic B6.A-(rs3676616-D10Ut...
Saved in:
Main Authors: | , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2019-01-01
|
Series: | Journal of Nutrition and Metabolism |
Online Access: | http://dx.doi.org/10.1155/2019/8594825 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|