Weissella cibaria suppresses colitis-associated colorectal cancer by modulating the gut microbiota-bile acid-FXR axis

Weissella cibaria suppresses colitis-associated colorectal cancer by modulating the gut microbiota-bile acid-FXR axis

ABSTRACT Gut microbiota dysbiosis critically contributes to colitis-associated colorectal cancer (CAC) pathogenesis, positioning microbial modulation as a promising therapeutic strategy. Weissella cibaria (W. cibaria) is an emerging probiotic with potential cancer-inhibiting effects. This study inve...

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Bibliographic Details
Main Authors: Qiuyao Hao, Fei Huang, Liangzheng Chang, Hongyuan Dai, Weiwei Chen, Yiran Yao, Yunhuan Zhen
Format: Article
Language:English
Published: American Society for Microbiology 2025-07-01
Series:mSystems
Subjects:
Weissella cibaria
bile acid
FXR
colitis-associated colorectal cancer
gut microbiota
Online Access:https://journals.asm.org/doi/10.1128/msystems.00288-25
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https://journals.asm.org/doi/10.1128/msystems.00288-25

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