Optical control of sphingolipid biosynthesis using photoswitchable sphingosines

Optical control of sphingolipid biosynthesis using photoswitchable sphingosines

Sphingolipid metabolism comprises a complex interconnected web of enzymes, metabolites, and modes of regulation that influence a wide range of cellular and physiological processes. Deciphering the biological relevance of this network is challenging as numerous intermediates of sphingolipid metabolis...

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Bibliographic Details
Main Authors: Matthijs Kol, Alexander J.E. Novak, Johannes Morstein, Christian Schröer, Tolulope Sokoya, Svenja Mensing, Sergei M. Korneev, Dirk Trauner, Joost C.M. Holthuis
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Journal of Lipid Research
Subjects:
azobenzene
budding yeast
cell-free expression
ceramide synthase
chemical synthesis
click chemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227524002293
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