Phase 1 study of quercetin, a natural antioxidant for children and young adults with Fanconi anemia

Phase 1 study of quercetin, a natural antioxidant for children and young adults with Fanconi anemia

Abstract: Fanconi anemia (FA) is a rare inherited disorder characterized by progressive bone marrow failure (BMF) and a predisposition to malignancy. Systemic reactive oxygen species (ROS) and increased sensitivity of FA hematopoietic progenitors to ROS play a key role in the pathogenesis of BMF. Tr...

Full description

Saved in:
Bibliographic Details
Main Authors: Parinda A. Mehta, Adam Nelson, Sara Loveless, Adam Lane, Tsuyoshi Fukuda, Ashley Teusink-Cross, Deborah Elder, Denise Lagory, Erica Miller, Jose A. Cancelas, Jonathan Howell, Junfang Zhao, Kana Mizuno, Kasiani C. Myers, Kelly Lake, Kelly McIntosh, Kenneth D. R. Setchell, Nathan Luebbering, Stephanie Edwards, Tafadzwa Chihanga, Susanne I. Wells, Stella M. Davies
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952925000308
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S2473952925000308

Similar Items