Phase-dependent closed-loop deep brain stimulation of the fornix provides bidirectional manipulation of hippocampal theta oscillations

Introduction: Alzheimer's disease (AD) has very limited treatment options and therapies to prevent or reverse neurodegeneration remain elusive. Deep brain stimulation (DBS), whereby high-frequency pulses of electricity are delivered continuously to a specific part of the brain, has been trialle...

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Bibliographic Details
Main Authors: Isaac Grennan, Brook Perry, Anna Verghese, Melissa Jones, Oliver Härmson, Colin G. McNamara, Andrew Sharott
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Brain Stimulation
Online Access:http://www.sciencedirect.com/science/article/pii/S1935861X25001007
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