The Anti-Inflammatory Activity of a Novel Fused-Cyclopentenone Phosphonate and Its Potential in the Local Treatment of Experimental Colitis
A novel fused-cyclopentenone phosphonate compound, namely, diethyl 3-nonyl-5-oxo-3,5,6,6a-tetrahydro-1H-cyclopenta[c]furan-4-ylphosphonate (P-5), was prepared and tested in vitro (LPS-activated macrophages) for its cytotoxicity and anti-inflammatory activity and in vivo (DNBS induced rat model) for...
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Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2015-01-01
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Series: | Gastroenterology Research and Practice |
Online Access: | http://dx.doi.org/10.1155/2015/939483 |
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